Spatial and temporal coordination of traction forces in one-dimensional cell migration
نویسندگان
چکیده
منابع مشابه
Spatial and temporal coordination of traction forces in one-dimensional cell migration.
Migration of a fibroblast along a collagen fiber can be regarded as cell locomotion in one-dimension (1D). In this process, a cell protrudes forward, forms a new adhesion, produces traction forces, and releases its rear adhesion in order to advance itself along a path. However, how a cell coordinates its adhesion formation, traction forces, and rear release in 1D migration is unclear. Here, we ...
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Whereas the adhesion and migration of individual cells have been well described in terms of physical forces, the mechanics of multicellular assemblies is still poorly understood. Here, we study the behavior of epithelial cells cultured on microfabricated substrates designed to measure cell-to-substrate interactions. These substrates are covered by a dense array of flexible micropillars whose de...
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ژورنال
عنوان ژورنال: Cell Adhesion & Migration
سال: 2016
ISSN: 1933-6918,1933-6926
DOI: 10.1080/19336918.2016.1221563